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For the safest results, do not mix Generic Viagra Soft Gel Caps with alcohol and avoid using Generic Viagra Soft Gel Caps with recreational drugs like amyl or butyl.By using this site, you agree to the Terms of Use and Privacy Policy.

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Sildenafil should not be used if sexual activity is inadvisable due to underlying cardiovascular risk factors (such as recent heart surgery, stroke or heart attack, etc.).

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What links here Related changes Upload file Special pages Permanent link Page information Wikidata item Cite this page.Viagra (sildenafil) is used to treat erectile dysfunction or impotence in men.Men with low testosterone levels who suffer from erectile dysfunction and have tried Viagra without success may benefit from adding a testosterone gel to.

Care should be exercised by people who are also taking protease inhibitors for the treatment of HIV infection.Sildenafil is broken down in the liver by hepatic metabolism using cytochrome p450 enzymes, mainly CYP450 3A4(major route), but also by CYP2C9 (minor route) hepatic isoenzymes.

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There are also mouth spray preparations of sildenafil for faster onset of action.Professional athletes have been documented using sildenafil, believing the opening of their blood vessels will enrich their muscles.Other drugs that operate by the same mechanism include tadalafil (Cialis) and vardenafil (Levitra).

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The primary indication of sildenafil is treatment of erectile dysfunction (inability to sustain a satisfactory erection to complete intercourse).Trade names include Kamagra ( Ajanta Pharma ), Silagra ( Cipla ), Edegra ( Sun Pharmaceutical ), Penegra ( Zydus Cadila ), and Zenegra ( Alkem Laboratories ).Sildenafil protects cyclic guanosine monophosphate (cGMP) from degradation by cGMP-specific phosphodiesterase type 5 (PDE5) in the corpus cavernosum.It was initially studied for use in hypertension (high blood pressure) and angina pectoris (a symptom of ischaemic heart disease ).Consumer Medicine Information (CMI) about Viagra (sildenafil) intended for persons living in Australia.This metabolite also has an affinity for the PDE receptors, about 40% of that of sildenafil.